Field comparison of hydrogen peroxide measuring systems for isolators

A consultant received an HPP272 probe from Vaisala in combination with the Indigo 201 transmitter for testing purposes. In his work, he not only qualifies for devices and environments, but also for biodecontamination cycles and protocols. When he was given the opportunity to evaluate the Vaisala hydrogen peroxide probe in combination with the Indigo 201 transmitter, he may have been using his current hydrogen peroxide (H2O2) meter.
The first big difference is that the sensor is only delivered per million readings (ppm), while the HPP272 probe has been configured with the Indigo 201 transmitter to deliver three values: H2O2 concentration in ppm, percentage relative saturation (Humidity) and temperature. Vaisala Nord has two probes for hydrogen peroxide measurement. The HPP271 probe can only contain the H2O2 concentration in ppm and the HPP272 probe can contain various parameters, including the H2O2 concentration in ppm, relative saturation, relative humidity, temperature, dew point and vapor pressure. "Since my standard sensor as well as the Vaisala HPP272 is less than a foot away in the isolator, I started the decontamination cycle," he said. “The electrochemical H2O2 concentration sensor initially responds faster, but within five to ten minutes. The number value for the H2O2 concentration is also not important of the relative cycle of cycle. Both units were consistent throughout the validation. "
While the concentration values ​​were similar, the resolution of the values ​​differed. Towards the end of the decontamination phase, both units showed almost identical values
The Vaisala unit provides moisture, temperature and H2O2 concentration. He believes that knowing the environmental parameters along with the H2O2 ppm values ​​is effective.
He said: "If we can influence the process with consistent biodecontamination cycles with a better understanding of the critical parameters, this will result in more efficient manufacturing."
One of the parameters that was new to him was the relative saturation percentage that occurred at 82% RS.
By comparing Vaisala's electrochemical meters and HPP272 probe in combination with the Indigo 201 transmitter, several advantages of the Vaisala system are identified, particularly the resolution of the ppm measurement and the relative saturation value.